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Article

Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS.

Neurobiology of aging - 1 Aug 2009

Gijselinck Ilse, Sleegers Kristel, Engelborghs Sebastiaan, Robberecht Wim, Martin Jean-Jacques, Vandenberghe Rik, Sciot Raf, Dermaut Bart, Goossens Dirk, van der Zee Julie, De Pooter Tim, Del-Favero Jurgen, Santens Patrick, De Jonghe Peter, De Deyn Peter P, Van Broeckhoven Christine, Cruts Marc

Abstract excerpt

The nuclear TAR DNA binding protein (TDP-43) is deposited in ubiquitin-positive inclusions in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), two clinicopathologically overlapping neurodegenerative diseases. In this study we excluded mutations and copy number variations in...

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Identifiers

PMID: 18068872
DOI: 10.1016/j.neurobiolaging.2007.11.002

Genes

TARDBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18068872-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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