Article
TDP-43 gene analysis in frontotemporal lobar degeneration.
Neuroscience letters - 23 May 2007
Rollinson Sara, Snowden Julie S, Neary David, Morrison Karen E, Mann David M A, Pickering-Brown Stuart M
Abstract excerpt
It has recently been established that the ubiquitinated neuronal inclusions and neurites observed in frontotemporal lobar degeneration (FTLD) contain the TAR DNA-binding protein, TDP-43. It is not uncommon for genetic variation of genes that encode proteins that accumulate in neurodegenerative co...
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