Article
Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.
Genes, chromosomes & cancer - 1 Sept 2008
Scotto Luigi, Narayan Gopeshwar, Nandula Subhadra V, Arias-Pulido Hugo, Subramaniyam Shivakumar, Schneider Achim, Kaufmann Andreas M, Wright Jason D, Pothuri Bhavana, Mansukhani Mahesh, Murty Vundavalli V
Abstract excerpt
Recurrent karyotypic abnormalities are a characteristic feature of cervical cancer (CC) cells, which may result in deregulated expression of important genes that contribute to tumor initiation and progression. To examine the role of gain of the long arm of chromosome 20 (20q), one of the common chromosomal gains in CC, we evaluated CC at various stages of progression using single nucleotide polymorphism (SNP)...
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