Article
Blunted cardiac responses to receptor activation in subjects with Thr164Ile beta(2)-adrenoceptors.
Circulation - 27 Feb 2001
Brodde O E, Büscher R, Tellkamp R, Radke J, Dhein S, Insel P A
Abstract excerpt
BACKGROUND: Recent evidence indicates that certain genotypes of beta(2)-adrenoceptors (AR) may indicate an increased risk of cardiovascular disease or an increased rate of disease progression. Of particular importance, the Thr164Ile polymorphism, which is found in approximately 4% of humans, show...
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