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Article

Complement factor H 402H variant and reticular macular disease.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Aug 2011

Smith R Theodore, Merriam Joanna E, Sohrab Mahsa A, Pumariega Nicole M, Barile Gaetano, Blonska Anna M, Haans Raymond, Madigan David, Allikmets Rando

Abstract excerpt

OBJECTIVE: To determine the association of high-risk alleles in the complement factor H (CFH; Y402H, rs1061170) and age-related maculopathy susceptibility (ARMS2; A69S, rs10490924) genes with reticular macular disease (RMD), a major clinical subphenotype of age-related macular degeneration (AMD). METHODS: Using retinal images from the Columbia Macular Genetics Study, we identified 67 subject individuals with RMD....

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Source

Open in PubMed Open full text

Identifiers

PMID: 21825189
DOI: 10.1001/archophthalmol.2011.212
PMCID: PMC3767386

Genes

ARMS2
CFH

Variants

rs1061170
rs1061170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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