Article
Complement factor H increases risk for atrophic age-related macular degeneration.
Ophthalmology - 1 Sept 2006
Postel Eric A, Agarwal Anita, Caldwell Jennifer, Gallins Paul, Toth Cynthia, Schmidt Silke, Scott William K, Hauser Michael A, Haines Jonathan L, Pericak-Vance Margaret A
Abstract excerpt
OBJECTIVE: To determine if the complement factor H gene (CFH) determines risk for development of geographic atrophy (GA). DESIGN: Retrospective case-control study. PARTICIPANTS AND CONTROLS: The independent case-control data set contained 647 age-related macular degeneration (AMD) cases (grades 3, 4, or 5) and 163 controls (grades 1 or 2). METHODS: To determine if CFH had any effect on determining risk for...
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