Article
Use of a multi-thermal washer for DNA microarrays simplifies probe design and gives robust genotyping assays.
Nucleic acids research - 1 Feb 2008
Petersen Jesper, Poulsen Lena, Petronis Sarunas, Birgens Henrik, Dufva Martin
Abstract excerpt
DNA microarrays are generally operated at a single condition, which severely limits the freedom of designing probes for allele-specific hybridization assays. Here, we demonstrate a fluidic device for multi-stringency posthybridization washing of microarrays on microscope slides. This device is called a multi-thermal array washer (MTAW), and it has eight individually controlled heating zones, each of which...
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