Article
A mycolyl transferase mutant of Rhodococcus equi lacking capsule integrity is fully virulent.
Veterinary microbiology - 30 Apr 2008
Sydor Tobias, von Bargen Kristine, Becken Ulrike, Spuerck Sabine, Nicholson Vivian M, Prescott John F, Haas Albert
Abstract excerpt
Rhodococcus equi is a mucoid Gram-positive facultative intracellular pathogen which can cause severe bronchopneumonia in foals and AIDS patients. A polysaccharide capsule which gives R. equi a mucoid appearance has long been suspected to be a virulence factor. Here, we describe a transposome mutant in the gene fbpA of strain R. equi 103 causing absence of a capsular structure. FbpA is a chromosomal gene...
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