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Virulence Plasmid of<i>Rhodococcus equi</i>Contains Inducible Gene Family Encoding Secreted Proteins

1 Feb 2001

Abstract excerpt

Rhodococcus equi causes severe pyogranulomatous pneumonia in foals. This facultative intracellular pathogen produces similar lesions in immunocompromised humans, particularly in AIDS patients. Virulent strains of R. equi bear a large plasmid that is required for intracellular survival within macrophages and for virulence in foals and mice. Only two plasmid-encoded proteins have been described previously; a 15- to...

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PMID: 11159951
DOI: 10.1128/iai.69.2.650-656.2001

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