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Necrotic Death ofRhodococcus equi-Infected Macrophages Is Regulated by Virulence-Associated Plasmids

24 Jan 2004

Abstract excerpt

Rhodococcus equi is a gram-positive intracellular pathogen that can cause severe bronchopneumonia in foals and AIDS patients. It has been reported that advanced infection of foals is characterized by tissue necrosis, coinciding with the presence of degenerate bacteria-laden macrophages. Here, we report that the possession of the VapA-expressing plasmid, which has been previously correlated with a high level of...

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PMID: 14742529
DOI: 10.1128/iai.72.2.853-862.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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