Article
Matrix metalloproteinase-2, -9, and -12 gene polymorphisms in generalized aggressive periodontitis.
Journal of periodontology - 1 Dec 2007
Gürkan Ali, Emingil Gülnur, Saygan Buket Han, Atilla Gül, Cinarcik Serhat, Köse Timur, Berdeli Afig
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) are involved in periodontal tissue remodeling and degradation. Polymorphisms in the promoter region of the MMP-2 and -9 genes and in the coding region of the MMP-12 gene could affect transcription and the function of these enzymes. The aim of the present study was to determine the association between the aforementioned MMP polymorphisms and generalized aggressive...
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