Article
Hepatic iron overload and risk of hepatocellular carcinoma in cirrhosis.
Gastroenterologie clinique et biologique - 1 Jan 2010
Nahon P, Ganne-Carrié N, Trinchet J-C, Beaugrand M
Abstract excerpt
Iron accumulation in the liver is considered to be a co-factor for progression of liver disease. Iron overload can enhance the effects of oxidative stress and influence the natural history of patients with cirrhosis, exposing them to a higher risk of hepatocellular carcinoma. The results of clinical studies designed to assess the impact of liver iron content on the risk of tumor development have remained...
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