Article
HFE gene mutations in alcoholic and virus-related cirrhotic patients with hepatocellular carcinoma.
The American journal of gastroenterology - 1 Apr 2002
Lauret Eugenia, Rodríguez Manuel, González Segundo, Linares Antonio, López-Vázquez Antonio, Martínez-Borra Jesús, Rodrigo Luis, López-Larrea Carlos
Abstract excerpt
OBJECTIVE: The increased risk of developing hepatocellular carcinoma in hereditary hemochromatosis has been associated with cirrhosis and hepatic iron overload. The aim of this study was to investigate the association between HFE gene mutations (C282Y, H63D) and hepatocellular carcinoma in patients with alcoholic and virus-related cirrhosis. METHODS: Serum markers of iron status and HFE mutations were determined...
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