Article
A genomic background based method for association analysis in related individuals.
PloS one - 5 Dec 2007
Amin Najaf, van Duijn Cornelia M, Aulchenko Yurii S
Abstract excerpt
BACKGROUND: Feasibility of genotyping of hundreds and thousands of single nucleotide polymorphisms (SNPs) in thousands of study subjects have triggered the need for fast, powerful, and reliable methods for genome-wide association analysis. Here we consider a situation when study participants are genetically related (e.g. due to systematic sampling of families or because a study was performed in a genetically...
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