Article
Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome.
Leukemia - 1 Mar 2008
Jankowska A M, Gondek L P, Szpurka H, Nearman Z P, Tiu R V, Maciejewski J P
Abstract excerpt
In myelodysplastic syndromes (MDS) increased chromosomal breaks point toward defects in DNA repair machinery including base excision repair (BER) pathway involved in handling of oxidative DNA damage. We investigated whether defects in this pathway can be found in MDS. Elevated levels of 8-oxoguan...
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