Article
A case report: bone marrow mesenchymal stem cells from a Rett syndrome patient are prone to senescence and show a lower degree of apoptosis.
Journal of cellular biochemistry - 15 Apr 2008
Squillaro Tiziana, Hayek Giuseppe, Farina Ernesto, Cipollaro Marilena, Renieri Alessandra, Galderisi Umberto
Abstract excerpt
Rett syndrome (RTT) is one of the most common genetic diseases responsible for a progressive disabling neurodevelopmental disorder. Mutations in the MeCP2 gene were identified in the great majority of RTT patients. MeCP2 protein binds to methylated DNA and produces changes in chromatin structure....
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