Article
Depression in Alzheimer's disease might be associated with apolipoprotein E epsilon 4 allele frequency in women but not in men.
Dementia and geriatric cognitive disorders - 1 Jan 2002
Müller-Thomsen Thomas, Arlt Sönke, Ganzer Stefanie, Mann Ulrike, Mass Reinhard, Naber Dieter, Beisiegel Ulrike
Abstract excerpt
The association between depression and apolipoprotein E (apoE) was investigated in 137 out-patients with Alzheimer's disease. An ICD-10 diagnosis of depression was found in 21.1% of all patients. There was a good correlation between clinicians' diagnoses and blinded rating by the Montgomery-Asberg Depression Rating Scale (r = 0.70). In male patients, apoE 3/3 was detected in 34.1%, 3/4 in 38.6%, 4/4 in 13.6%, 2/4...
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