Article
Animal type 1 cryptochromes. Analysis of the redox state of the flavin cofactor by site-directed mutagenesis.
The Journal of biological chemistry - 8 Feb 2008
Öztürk Nuri, Song Sang-Hun, Selby Christopher P, Sancar Aziz
Abstract excerpt
It has recently been realized that animal cryptochromes (CRYs) fall into two broad groups. Type 1 CRYs, the prototype of which is the Drosophila CRY, that is known to be a circadian photoreceptor. Type 2 CRYs, the prototypes of which are human CRY 1 and CRY 2, are known to function as core clock proteins. The mechanism of photosignaling by the Type 1 CRYs is not well understood. We recently reported that the...
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