Article
Differing phenotypes between intraepithelial and stromal lymphocytes in early-stage tongue cancer.
Cancer research - 1 Dec 2007
Katou Fuminori, Ohtani Haruo, Watanabe Yoshiko, Nakayama Takashi, Yoshie Osamu, Hashimoto Kenji
Abstract excerpt
The significance of tumor-infiltrating lymphocytes (TIL) has attracted much attention in relation to the prognosis of patients. We herein examined the activation status of the TILs in relation to the tumor microenvironment. By using frozen sections of human early-stage tongue cancers (n = 22), the TILs in the cancer nests and those in the cancer stroma were compared for the expression of PD-1, NKG2A, NKG2D, CD69,...
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