Article
Predominant Th2/Tc2 polarity of tumor-infiltrating lymphocytes in human cervical cancer.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2001
Sheu B C, Lin R H, Lien H C, Ho H N, Hsu S M, Huang S C
Abstract excerpt
Cytotoxic T lymphocytes (Tc) play a central role in cellular immunity against cancers. The cytotoxic potential of freshly isolated tumor-infiltrating lymphocytes (TILs) is usually not expressed. This suggests the possible existence of as yet unspecified and perhaps complex immunosuppressive factors or cytokines that affect the anti-tumor capacity of these TILs in the tumor milieu. In the present study, we...
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