Article
Physiology of schizophrenia, bipolar disorder, and schizoaffective disorder.
The American journal of psychiatry - 1 Dec 2007
Martin Laura F, Hall Mei-Hua, Ross Randal G, Zerbe Gary, Freedman Robert, Olincy Ann
Abstract excerpt
OBJECTIVE: Endophenotypes have been proposed to identify the genetic and biological substrates of complex disorders. Three physiological inhibitory endophenotypes of large effect size in schizophrenia include suppression of P50 auditory evoked responses, inhibition of leading (small anticipatory) saccades during smooth pursuit eye movements, and cancellation of reflexive saccades in the antisaccade eye movement...
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