Eye movement dysfunction in first-degree relatives of patients with schizophrenia: a meta-analytic evaluation of candidate endophenotypes.

doi:10.1016/j.bandc.2008.09.001

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Article

Eye movement dysfunction in first-degree relatives of patients with schizophrenia: a meta-analytic evaluation of candidate endophenotypes.

Brain and cognition - 1 Dec 2008

Calkins Monica E, Iacono William G, Ones Deniz S

Abstract excerpt

Several forms of eye movement dysfunction (EMD) are regarded as promising candidate endophenotypes of schizophrenia. Discrepancies in individual study results have led to inconsistent conclusions regarding particular aspects of EMD in relatives of schizophrenia patients. To quantitatively evaluate and compare the candidacy of smooth pursuit, saccade and fixation deficits in first-degree biological relatives, we...

Topics

Eye Movements
Family
Fixation, Ocular
Genetic Predisposition to Disease
Humans
Phenotype
Psychomotor Performance
Saccades
Schizophrenia

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PMID: 18930572
DOI: 10.1016/j.bandc.2008.09.001
PMCID: PMC4654966

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