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Article

Prospects for DNA-based prenatal diagnosis of mitochondrial disorders.

Prenatal diagnosis - 1 Dec 1996

Poulton J, Marchington D R

Abstract excerpt

Mitochondria have their own DNA which is maternally inherited. Mitochondrial DNA (mtDNA) diseases are extremely variable because of the genetics of mtDNA and the unique pathogenesis of these disorders. This makes predicting the prognosis and the transmission of mtDNA disorders difficult. While mtDNA polymorphisms at a single base position are common, the overwhelming majority of the mitochondrial genomes within a...

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PMID: 9061755
DOI: 10.1002/(SICI)1097-0223(199612)16:13<1247::AID-PD99>3.0.CO;2-P

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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