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Article

A deoxyribozyme with a novel guanine quartet-helix pseudoknot structure.

Journal of molecular biology - 25 Jan 2008

McManus Simon A, Li Yingfu

Abstract excerpt

Here we report a deoxyribozyme with a unique structure that contains a two-tiered guanine quadruplex interlinked to a Watson-Crick duplex. Through in vitro selection, sequence mutation, and methylation interference, we show the presence of both the two-tiered guanine-quadruplex and two helical regions contained in the active structure of this self-phosphorylating deoxyribozyme. Interestingly, one GG element of...

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Identifiers

PMID: 18054790
DOI: 10.1016/j.jmb.2007.10.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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