Association of estrogen receptor 2 gene polymorphisms with obesity in women (obesity and estrogen receptor 2 gene).

Abstract excerpt

OBJECTIVE: Few studies have examined the association between genetic variants of the estrogen receptor beta (ESR2) and obesity in postmenopausal women. METHODS: The relationship of three polymorphisms (rs1271572, rs1256049 and rs4986938) and their associated haplotypes in the ESR2 gene with obesity and overweight were evaluated in 561 apparently healthy women (median age 63 years) from the Women's Health Study....