Article
Roles of Streptococcus mutans dextranase anchored to the cell wall by sortase.
Oral microbiology and immunology - 1 Apr 2004
Igarashi T, Asaga E, Goto N
Abstract excerpt
In order to clarify the role that sortase (SrtA) plays in anchoring dextranase (Dex) to the cell wall of Streptococcus mutans, both Dex- and SrtA- mutants were constructed by insertional inactivation of the respective genes. Western blot analysis with a Dex antiserum showed that in the srtA mutant the Dex was not bound to the cell wall but was secreted into the culture supernatant. In contrast, in the wild type,...
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