Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of candidate genes that influence sex hormone-dependent disease phenotypes in mouse lupus.

Genes and immunity - 1 Jan 2008

Gubbels Bupp M R, Jørgensen T N, Kotzin B L

Abstract excerpt

Ninety percent of systemic lupus erythematosus patients are female, and gender differences in lupus susceptibility are also observed in (New Zealand Black x New Zealand White)F1 (BWF1) lupus-prone mice. We followed orchiectomized, intact male and female BWF1 mice for lupus-like disease for 1 year. A comparative gene expression analysis was then used to identify candidate genes potentially responsible for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Disease Models, Animal
Share to Gonadal Steroid Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lupus Erythematosus, Systemic

Share to Mice, Inbred NZB

Share to Orchiectomy

Share to Sex Chromosomes

Source

Identifiers

PMID: 18046341
DOI: 10.1038/sj.gene.6364447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of candidate genes that influence sex hormone-dependent disease phenotypes in mouse lupus.PMID 18046341Read ↗

Sex differences in the expression of lupus-associated miRNAs in splenocytes from lupus-prone NZB/WF1 miceSemantic proximity Read ↗

Gender differences of B cell signature related to estrogen-induced IFI44L/BAFF in systemic lupus erythematosusSemantic proximity Read ↗

Linking susceptibility genes and pathogenesis mechanisms using mouse models of systemic lupus erythematosus.Semantic proximity Read ↗

Single cell RNA sequencing reveals ferritin as a key mediator of autoimmune pre-disposition in a mouse model of systemic lupus erythematosus.Semantic proximity Read ↗

Susceptibility genes in the pathogenesis of murine lupus.Semantic proximity Read ↗

Sex bias in systemic lupus erythematosus: a molecular insightSemantic proximity Read ↗

Sex hormones and SLE: influencing the fate of autoreactive B cells.Semantic proximity Read ↗

Gender-dependent Expression of Murine Irf5 Gene: Implications for Sex Bias in AutoimmunitySemantic proximity Read ↗

Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility.Semantic proximity Read ↗

Autosomal loci associated with a sex-related difference in the development of autoimmune phenotypes in a lupus model.Semantic proximity Read ↗

Gender bias in lupus: does immune response initiated in the gut mucosa have a role?Semantic proximity Read ↗

Sexual Dimorphism in Gene Expression: A Genome-Wide Study of Tissue and Chromosome DependenciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.