Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.

Diabetologia - 1 Mar 2008

Franks P W, Rolandsson O, Debenham S L, Fawcett K A, Payne F, Dina C, Froguel P, Mohlke K L, Willer C, Olsson T, Wareham N J, Hallmans G, Barroso I, Sandhu M S

Abstract excerpt

AIMS/HYPOTHESIS: Mutations at the gene encoding wolframin (WFS1) cause Wolfram syndrome, a rare neurological condition. Associations between single nucleotide polymorphisms (SNPs) at WFS1 and type 2 diabetes have recently been reported. Thus, our aim was to replicate those associations in a northern Swedish case-control study of type 2 diabetes. We also performed a meta-analysis of published and previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Europe

Share to Genetic Variation

Share to Linkage Disequilibrium

Share to Membrane Proteins

Share to Risk Assessment

Share to Sweden

Source

Open in PubMed Open full text

Identifiers

PMID: 18040659
DOI: 10.1007/s00125-007-0887-6
PMCID: PMC2670195

Genes

WFS1

Variants

rs10010131

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of the association between variants in WFS1 and risk of type 2 diabetes in European populations.PMID 18040659Read ↗

A WFS1 haplotype consisting of the minor alleles of rs752854, rs10010131, and rs734312 shows a protective role against type 2 diabetes in Russian patients.Semantic proximity Read ↗

Association of rs734312 and rs10010131 polymorphisms in WFS1 gene with type 2 diabetes mellitus: a meta-analysis.Semantic proximity Read ↗

Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 MutationSemantic proximity Read ↗

Common variants in WFS1 confer risk of type 2 diabetes.Semantic proximity Read ↗

Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk.Semantic proximity Read ↗

Association study of the effect of WFS1 polymorphisms on risk of type 2 diabetes in Japanese population.Semantic proximity Read ↗

Association studies of genetic variation in the WFS1 gene and type 2 diabetes in U.K. populations.Semantic proximity Read ↗

Clinical and genetic analysis of two wolfram syndrome families with high occurrence of wolfram syndrome and diabetes type II: a case report.Semantic proximity Read ↗

Wolfram syndrome in the Polish population: novel mutations and genotype-phenotype correlation.Semantic proximity Read ↗

Novel WFS1 variants are associated with different diabetes phenotypesSemantic proximity Read ↗

A novel WFS1 variant associated with severe diabetic retinopathy in Wolfram syndrome type 1.Semantic proximity Read ↗

Testing of diabetes-associated WFS1 polymorphisms in the Diabetes Prevention Program.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.