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Article

Association study of the effect of WFS1 polymorphisms on risk of type 2 diabetes in Japanese population.

The Kobe journal of medical sciences - 30 Oct 2008

Mita Masaki, Miyake Kazuaki, Zenibayashi Masako, Hirota Yushi, Teranishi Tetsuya, Kouyama Kunichi, Sakaguchi Kazuhiko, Kasuga Masato

Abstract excerpt

Mutations of WFS1 gene cause Wolfram syndrome, which is a rare autosomal recessive disorder characterized by juvenile diabetes mellitus, optic atrophy, deafness and diabetes insipidus. The product encoded by WFS1 gene, wolframin, could be involved in ER stress response causing beta-cell loss thro...

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Identifiers

PMID: 19258739

Genes

WFS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19258739-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association study of the effect of WFS1 polymorphisms on risk of type 2 diabetes in Japanese population.PMID 19258739Read ↗

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