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Article

Novel long-lasting interferon alpha derivatives designed by glycoengineering.

Biochimie - 1 Mar 2008

Ceaglio N, Etcheverrigaray M, Kratje R, Oggero M

Abstract excerpt

Human alpha interferons (hIFN-alpha) comprise a family of closely related proteins that block viral infection, inhibit cell proliferation and modulate cell differentiation. Recombinant hIFN-alpha2 has proved useful for the treatment of a variety of human viral diseases and cancers. However, the clinical use of this cytokine has been restricted due to its short circulating half-life, which makes frequent dosing...

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Identifiers

PMID: 18039474
DOI: 10.1016/j.biochi.2007.10.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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