Article
Routine fetal RHD genotyping with maternal plasma: a four-year experience in Belgium.
Transfusion - 1 Feb 2008
Minon Jean-Marc, Gerard Christiane, Senterre Jean-Marc, Schaaps Jean-Pierre, Foidart Jean-Michel
Abstract excerpt
BACKGROUND: The objective was to evaluate the diagnostic value of RHD fetal genotyping from the plasma of D- mothers as soon as 10 weeks' gestation in a routine clinical practice in Belgium. STUDY DESIGN AND METHODS: A prospective study was conducted between November 2002 and December 2006. DNA extraction was performed in an automated closed tube system. Fetal RHD/SRY genotypes were detected in the plasma of 563...
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