Article
Association between GSTM1 and GSTT1 allelic variants and head and neck squamous cell cancinoma.
PloS one - 1 Jan 2012
Zhang Yang, Ni Yuanyuan, Zhang Hao, Pan Yongchu, Ma Junqing, Wang Lin
Abstract excerpt
BACKGROUNDS: GSTM1 and GSTT1 are involved in the detoxification of carcinogens such as smoking by-products, and polymorphisms in these two genes with a result of loss of enzyme activity may increase risk of carcinogenesis. Although many epidemiological studies have investigated the association between GSTM1 or GSTT1 null genotype and head and neck squamous cell carcinoma (HNSCC), the results remain conflicting....
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