Article
Glutathione S-transferase T1 null polymorphism and the risk for head and neck cancer.
Acta oto-laryngologica - 1 Mar 2006
Oude Ophuis Michel B, Manni Johannes J, Peters Wilber H M
Abstract excerpt
CONCLUSIONS: Inter-regional differences in the distribution of genetic polymorphisms in glutathione S-transferases (GSTs) exist, which may have significant effect on the outcome of other GST polymorphism studies. The GSTT1 null genotype appears to be involved in modulation of the risk for head and neck squamous cell carcinoma (HNSCC). BACKGROUND: The risk of HNSCC is strongly associated with smoking of cigarettes...
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