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Article

Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco and betel quid.

International journal of cancer - 15 Mar 2008

Lee Chien-Hung, Lee Jang-Ming, Wu Deng-Chyang, Goan Yih-Gang, Chou Shah-Hwa, Wu I-Chen, Kao Ein-Long, Chan Te-Fu, Huang Meng-Chuan, Chen Pei-Shih, Lee Chun-Ying, Huang Chia-Tsuan, Huang Hsiao-Ling, Hu Chih-Yang, Hung Yu-Hsiu, Wu Ming-Tsang

Abstract excerpt

The consumption of alcohol, tobacco and betel quid has been found to be an important contributor to esophageal squamous cell carcinoma (ESCC) in Taiwan. The genotoxic effect of the ADH1B and ALDH2 genes modulating an individual's alcohol-metabolizing capacity on ESCC may be linked to drinking beh...

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Source

Identifiers

PMID: 18033686
DOI: 10.1002/ijc.23264

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18033686-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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