Article
Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells.
Experimental hematology - 1 Feb 2008
Wang Yan-Yi, Deng Xingming, Xu Lijun, Gao Fengqin, Flagg Tammy, May W Stratford
Abstract excerpt
Bcl2 is a potent antiapoptotic gene that can increase resistance of adult bone marrow hematopoietic progenitor cells to lethal irradiation, and thereby preserve their ability to differentiate. However, the effect of Bcl2 on murine embryonic stem (ES) cells induced to undergo hematopoietic differentiation in the absence of a toxic stress is not known. To test this, murine CCE-ES cells that can be induced to...
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