Article
Genomewide linkage survey of nicotine dependence phenotypes.
Drug and alcohol dependence - 1 Mar 2008
Sullivan Patrick F, Kuo Po-Hsiu, Webb B Todd, Neale Michael C, Vittum Jen, Furberg Helena, Walsh Dermot, Patterson Diana G, Riley Brien, Prescott Carol A, Kendler Kenneth S
Abstract excerpt
BACKGROUND: A comprehensive understanding of the etiology and neurobiology of nicotine dependence is not available. We sought to identify genomic regions that might contain etiologically-relevant loci using genomewide univariate and bivariate linkage analyses. METHODS: We conducted secondary data analyses of 626 all possible sibling pairs ascertained in Ireland and Northern Ireland on the basis of alcohol...
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