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Article

Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas.

Genes, chromosomes & cancer - 1 Feb 2008

Helsing Per, Nymoen Dag Andre, Ariansen Sarah, Steine Solrun J, Maehle Lovise, Aamdal Steinar, Langmark Frøydis, Loeb Mitchell, Akslen Lars A, Molven Anders, Andresen Per Arne

Abstract excerpt

The presence of multiple primary cutaneous melanomas (MPM) has been advocated as guidance to identifying melanoma families. Frequencies of CDKN2A mutations in materials of sporadic MPM cases from pigmented lesion clinics vary between 8 and 15%. Patients with MPM have therefore been regarded as good candidates for CDKN2A mutational screening. We describe a population-based study where all persons in Norway...

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Identifiers

PMID: 18023021
DOI: 10.1002/gcc.20518

Genes

CDK4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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