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Article

Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma.

Archives of dermatology - 1 Sept 2000

Tsao H, Zhang X, Kwitkiwski K, Finkelstein D M, Sober A J, Haluska F G

Abstract excerpt

BACKGROUND: In patients with cutaneous melanoma, early age at disease onset is characteristic in familial cases and in individuals with multiple primary melanomas. Both subsets of patients with melanoma are at risk for harboring germline CDKN2A or CDK4 mutations. OBJECTIVE: We set out to prospectively determine the prevalence of CDKN2A and CDK4 mutations in a group of young patients with melanoma. DESIGN: We...

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Source

Identifiers

PMID: 10987867
DOI: 10.1001/archderm.136.9.1118

Genes

CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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