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Article

Spatially and genetically distinct African Trypanosome virulence variants defined by host interferon-gamma response.

The Journal of infectious diseases - 1 Dec 2007

Maclean Lorna, Odiit Martin, Macleod Annette, Morrison Liam, Sweeney Lindsay, Cooper Anneli, Kennedy Peter G E, Sternberg Jeremy M

Abstract excerpt

We describe 2 spatially distinct foci of human African trypanosomiasis in eastern Uganda. The Tororo and Soroti foci of Trypanosoma brucei rhodesiense infection were genetically distinct as characterized by 6 microsatellite and 1 minisatellite polymorphic markers and were characterized by differences in disease progression and host-immune response. In particular, infections with the Tororo genotype exhibited an...

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Identifiers

PMID: 18008245
DOI: 10.1086/522011
PMCID: PMC2082664

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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