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Article

Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection.

Infection and immunity - 1 Mar 2010

Morrison Liam J, McLellan Sarah, Sweeney Lindsay, Chan Chi N, MacLeod Annette, Tait Andy, Turner C Michael R

Abstract excerpt

The postgenomic era has revolutionized approaches to defining host-pathogen interactions and the investigation of the influence of genetic variation in either protagonist upon infection outcome. We analyzed pathology induced by infection with two genetically distinct Trypanosoma brucei strains and found that pathogenesis is partly strain specific, involving distinct host mechanisms. Infections of BALB/c mice with...

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Identifiers

PMID: 20086091
DOI: 10.1128/IAI.00943-09
PMCID: PMC2825911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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