Article
A spectrum of disease in human African trypanosomiasis: the host and parasite genetics of virulence.
Parasitology - 1 Dec 2010
Sternberg Jeremy M, Maclean Lorna
Abstract excerpt
For over 50 years it has been known that there are considerable differences in the severity and rate of progression of both Trypanosoma brucei rhodesiense and T. b. gambiense infection between individuals. Yet research into the factors, whether parasite or host, which control virulence in Human African trypanosomiasis is in its infancy. In this paper we review the clinical evidence for virulence variation and the...
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