Article
Genetic diversity and population structure of Trypanosoma brucei in Uganda: implications for the epidemiology of sleeping sickness and Nagana.
PLoS neglected tropical diseases - 1 Feb 2015
Echodu Richard, Sistrom Mark, Bateta Rosemary, Murilla Grace, Okedi Loyce, Aksoy Serap, Enyioha Chineme, Enyaru John, Opiyo Elizabeth, Gibson Wendy, Caccone Adalgisa
Abstract excerpt
BACKGROUND: While Human African Trypanosomiasis (HAT) is in decline on the continent of Africa, the disease still remains a major health problem in Uganda. There are recurrent sporadic outbreaks in the traditionally endemic areas in south-east Uganda, and continued spread to new unaffected areas in central Uganda. We evaluated the evolutionary dynamics underpinning the origin of new foci and the impact of host...
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