Article
BRCA1 and BRCA2 mutations in an Asian clinic-based population detected using a comprehensive strategy.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2007
Ang Peter, Lim Irene H K, Lee Tze-Chuen, Luo Jie-Ting, Ong Danny C T, Tan Puay Hoon, Lee Ann S G
Abstract excerpt
BACKGROUND AND OBJECTIVE: Genetic testing for germ line mutations in the BRCA1 and BRCA2 genes for some families at high risk for breast and/or ovarian cancer may yield negative results due to unidentified mutations or mutations with unknown clinical significance. We aimed to accurately determine the prevalence of mutations in these genes in an Asian clinic-based population by using a comprehensive testing...
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