Article
NMDA receptor NR2B subunit over-expression increases cerebellar granule cell migratory activity.
Journal of neurochemistry - 1 Feb 2008
Tárnok Krisztián, Czöndör Katalin, Jelitai Márta, Czirók András, Schlett Katalin
Abstract excerpt
Glutamate acting on NMDA receptors (NMDARs) is known to influence cerebellar granule cell migration. Subunit composition of NMDARs in granule cells changes characteristically during development: NR2B subunit containing receptors are abundant during migration towards the internal granule cell layer but are gradually replaced by NR2A and/or NR2C subunits once the final position is reached. Cerebellar granule cell...
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