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Article

Prognostic significance of HIF-1 alpha polymorphisms in transitional cell carcinoma of the bladder.

International journal of cancer - 15 Mar 2008

Nadaoka Junichi, Horikawa Yohei, Saito Mitsuru, Kumazawa Teruaki, Inoue Takamitsu, Narita Shintaro, Yuasa Takeshi, Satoh Shigeru, Nishiyama Hiroyuki, Ogawa Osamu, Tsuchiya Norihiko, Habuchi Tomonori

Abstract excerpt

Recently, two single nucleotide polymorphisms in the hypoxia-inducible factor-1 alpha (HIF-1 alpha) gene, P582S and A588T, were shown to cause significantly higher transcriptional activity than the wild type. We investigated the association between the HIF-1 alpha polymorphisms and the incidence and progression of transitional cell carcinoma of the bladder, and the relationship between the polymorphisms and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18000826
DOI: 10.1002/ijc.23256

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MVD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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