Article
Poxvirus DNA primase.
Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2007
De Silva Frank S, Lewis Whitney, Berglund Peter, Koonin Eugene V, Moss Bernard
Abstract excerpt
Poxviruses are large enveloped viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. At least six virus-encoded proteins are required for synthesis and processing of the double-stranded DNA genome of vaccinia virus, the prototype member of the family. One of these proteins, D5, is an NTPase that contains an N-terminal archaeoeukaryotic primase domain and a C-terminal superfamily III...
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