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Article

Mutational analysis of the resolution sequence of vaccinia virus DNA: essential sequence consists of two separate AT-rich regions highly conserved among poxviruses.

Journal of virology - 1 Oct 1990

Merchlinsky M

Abstract excerpt

In replicative forms of vaccinia virus DNA, the unit genomes are connected by palindromic junction fragments that are resolved into mature viral genomes with hairpin termini. Bacterial plasmids containing the junction fragment for vaccinia virus or Shope fibroma virus were converted into linear minichromosomes of vector sequence flanked by poxvirus hairpin loops after transfection into infected cells. Analysis of...

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Identifiers

PMID: 2398534
DOI: 10.1128/JVI.64.10.5029-5035.1990
PMCID: PMC247994

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