Mutational analysis of the resolution sequence of vaccinia virus DNA: essential sequence consists of two separate AT-rich regions highly conserved among poxviruses.

doi:10.1128/JVI.64.10.5029-5035.1990

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Article

Mutational analysis of the resolution sequence of vaccinia virus DNA: essential sequence consists of two separate AT-rich regions highly conserved among poxviruses.

Journal of virology - 1 Oct 1990

Merchlinsky M

Abstract excerpt

In replicative forms of vaccinia virus DNA, the unit genomes are connected by palindromic junction fragments that are resolved into mature viral genomes with hairpin termini. Bacterial plasmids containing the junction fragment for vaccinia virus or Shope fibroma virus were converted into linear m...

Topics

Base Composition
Base Sequence
Cell Line
DNA, Ribosomal
Genes, Viral
Humans
Molecular Sequence Data
Mutation
Plasmids
Poxviridae
Restriction Mapping
Vaccinia virus

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