Article
A novel PIP2 binding of epsilonPKC and its contribution to the neurite induction ability.
Journal of neurochemistry - 1 Sept 2007
Shirai Yasuhito, Murakami Takuya, Kuramasu Maho, Iijima Leo, Saito Naoaki
Abstract excerpt
Protein kinase C-epsilon (epsilonPKC) induces neurite outgrowth in neuroblastoma cells but molecular mechanism of the epsilonPKC-induced neurite outgrowth is not fully understood. Therefore, we investigated the ability of phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding of epsilonPKC and its correlation with the neurite extension. We found that full length epsilonPKC bound to PIP(2) in a...
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