Article
Complement factor H Y402H gene polymorphism and response to intravitreal bevacizumab in exudative age-related macular degeneration.
Acta ophthalmologica - 1 Jun 2011
Nischler Christian, Oberkofler Hannes, Ortner Christoph, Paikl Doris, Riha Wolfgang, Lang Nora, Patsch Wolfgang, Egger Stefan F
Abstract excerpt
PURPOSE: To determine whether different complement factor H (CFH) genotypes play a role in treatment of age-related macular degeneration (AMD) with intravitreal bevacizumab. METHODS: In this prospective study, we included 197 patients with exudative AMD and treated with 1.25 mg intravitreal bevacizumab at 6-week intervals until choroidal neovascularization (CNV) was no longer active. In all patients,...
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