Article
Codistribution of a sensory gating deficit and schizophrenia in multi-affected families.
Psychiatry research - 1 Dec 1991
Waldo M C, Carey G, Myles-Worsley M, Cawthra E, Adler L E, Nagamoto H T, Wender P, Byerley W, Plaetke R, Freedman R
Abstract excerpt
Because the clinical diagnosis of schizophrenia has not generally been an adequate phenotypic marker to detect the genes that convey risk for schizophrenia, efforts have been directed toward the identification of more elementary neuronal dysfunctions in schizophrenic patients and their families. Psychophysiological studies of sensory gating and selective attention suggest that defects in these brain functions are...
Topics
- Adult
- Arousal
- Attention
- Evoked Potentials, Auditory
- Humans
- Pedigree
- Phenotype
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenic Psychology